Pharmacologist (Microdialysis) - Nottingham
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Position Overview & Specifications
Sygnature Discovery is a leading independent integrated drug discovery and non-clinical services company. Private equity-backed since 2017, the company operates fully enabled research facilities in Nottingham and Alderley Park, UK, housing nearly 400 research scientists (over 80% of whom hold a PhD), and has an office presence in Cambridge, MA, and South San Francisco, CA, in the USA.
The In Vivo Pharmacology team at Sygnature Discovery play an essential role in supporting and leading integrated client projects as well as delivering specialist assays to complement In Vivo studies. The growing department is looking for talented scientists to push and lead our capabilities even further.
Your tasks as a Scientist within the CNS team will be varied and will involve customer support in planning and reporting of studies, daily operational work conducting in vivo microdialysis studies and expanding the capabilities of the team through the introduction of new technologies.
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Principal responsibilities will include:*
- Designing and planning in vivo pharmacology studies for CRO clients.
- Stereotaxic surgical procedures and administration of substances.
- Delivering high quality data and supporting documentation.
- Expanding the portfolio of technologies within the microdialysis area.
To succeed in the role, you will have the following capabilities and experience:
- A relevant education such as BSc in neuroscience, pharmacology, biology or similar.
- Ideally a PhD degree plus post-doctoral experience or experience in industry.
- Documented scientific experience within the in vivo neuroscience area in form of publications, talks.
- The proven ability and desire to carry out in vivo work (e.g. stereotaxic surgical procedures, administration of substances, behavioural experience).
- HPLC experience advantageous.
In return you will receive an excellent training and benefits package, including a highly competitive salary which is reviewed annually, a bonus scheme, a well-regarded pension scheme, and private medical insurance. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share in our success.
We also recognise that the environment you work in is a priority, so we have built a collaborative and supportive culture with plenty of opportunities to grow and succeed, tailored to individual and business needs. This includes an excellent set of bespoke training and development courses to accelerate both your scientific and personal career growth.
Since 2011, 34 compounds discovered by Sygnature for customers have entered pre-clinical development. So far, 17 of these have progressed to clinical trials (Phases I, II and III). In 2017, Sygnature Discovery received the prestigious Queenβs Award for Enterprise for International Trade, in 2020 the Medilink Outstanding Achievement Award, and in 2021 the Bionow Company of the Year Award.
For more information, visit www.sygnaturediscovery.com/careers.
If youβre interested in joining a company that places people at the heart of its business, please apply through the link and include:
1) Your CV
2) A covering letter that briefly outlines your suitability for the role and your current notice period (if applicable)
3) Confirmation of your status of eligibility to work in the UK (we can consider sponsoring potential employees with relevant levels of qualifications and experience under a Skilled Worker Visa).
Your application will be submitted through our trusted partners, Lever, but only employees of Sygnature Discovery will review your application and personal data.
We will be interviewing on an ongoing basis, so please submit your application as soon as possible. We look forward to hearing from you.
If you have any questions or need further information, please contact the Careers team at careers@sygnaturediscovery.com. Please do not submit your application to this email address.
Job Type: Full-time
Candidate Selection & Onboarding Process
Application & Resume Screening
Submit your tailored CV/Resume directly to the talent acquisition portal.
Technical & Competency Interviews
Virtual interviews with the hiring manager and multidisciplinary team.
Formal Offer & Benefits Negotiation
Written agreement outlining compensation, equity, retirement vesting, and relocation allowances.
Onboarding & Corporate Integration
Equipment provisioning, team orientation, and commencement of duties.
United Kingdom Right to Work & Skilled Worker Visa Guide
Employment in the United Kingdom requires legal Right to Work verified under the Home Office Points-Based Immigration System:
Sponsoring employers must hold an active Home Office A-rated Sponsor License and assign a valid Certificate of Sponsorship (CoS). Role must meet the general minimum salary threshold (Β£38,700) or occupation going rate.
Continuous employment under Skilled Worker status establishes eligibility for Indefinite Leave to Remain (ILR) after 5 continuous years, leading to British Citizenship.
Candidate Preparation Blueprint: General
Based on transatlantic hiring benchmarks for Pharmacologist (Microdialysis) - Nottingham roles across Sygnature Discovery Limited's corporate sector, successful applicants typically excel across three core dimensions:
Demonstrated portfolio evidence, architecture/system design case studies, or validated professional certifications directly applicable to General.
STAR method competency responses highlighting cross-functional leadership, conflict resolution, and delivering measurable enterprise ROI under tight timelines.
Total compensation expectation aligned within the benchmarked Salary Disclosed on Application bracket, including retirement vesting and health parity.
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